Former Regional Director: L. Pearl Mitchell*
Time of Service: 1st Great Lakes Regional Director, 1929-1930

Former Regional Director: Margaret Davis Bowen*
Time of Service: 2nd Great Lakes Regional Director, 1931

Former Regional Director: Mattie Dalton Jackson*
Time of Service: 3rd Great Lakes Regional Director, 1932-1934

Former Regional Director: Beulah T. Whitby*
Time of Service: 4th Great Lakes Regional Director, 1934-1946

Former Regional Director: Wilbretta Pope Johnson*
Time of Service: 5th Great Lakes Regional Director, 1937-1938

Former Regional Director: Irene A. Graves*
Time of Service: 6th Great Lakes Regional Director, 1938-1940

Former Regional Director: Juanita Davis Webster*
Time of Service: 7th Great Lakes Regional Director, 1941-1942

Former Regional Director: Laura Thelma Fife Lovelace*
Time of Service: 8th Great Lakes Regional Director, 1943-1946

Former Regional Director: Ruth M. Thomas Hargrave*
Time of Service: 9th Great Lakes Regional Director, 1948-1950

Former Regional Director: Fannette B. Norris*
Time of Service: 10th Great Lakes Regional Director, 1950-1954

Former Regional Director: Gwendolyn C. Goldston*
Time of Service: 11th Great Lakes Regional Director, 1954-1958

Former Regional Director: La Rue Frederick*
Time of Service: 12th Great Lakes Regional Director, 1958-1962

Former Regional Director: Bernice I. Sumlin*
Time of Service:13th Great Lakes Regional Director, 1962-1966

Former Regional Director: Thelma C. Hollis*
Time of Service: 14th Great Lakes Regional Director, 1966-1968

Former Regional Director: Altha C. Brown*
Time of Service:15th Great Lakes Regional Director, 1968-1972

Former Regional Director: Eva L. Evans, Ph.D.*
Time of Service: 16th Great Lakes Regional Director, 1972-1974

Former Regional Director: Madelyn H. Giddens*
Time of Service: 17th Great Lakes Regional Director, 1974-1978

Former Regional Director: Gloria S. Smith, Ph.D.
Time of Service: 18th Great Lakes Regional Director, 1978-1982

Former Regional Director: Bella G. Parker, Ph.D*
Time of Service: 19th Great Lakes Regional Director, 1982-1986

Former Regional Director: Ann C. Battles
Time of Service: 20th Great Lakes Regional Director, 1986-1988

Former Regional Director: Emma Lilly Henderson
Time of Service: 21st Great Lakes Regional Director, 1988-1990

Former Regional Director: Phyllis E. Robinson, Ph.D.
Time of Service: 22nd Great Lakes Regional Director, 1990-1994

Former Regional Director: Patricia Petty-Wilson
Time of Service: 23rd Great Lakes Regional Director, 1994-1998

Former Regional Director: Rachel E. Ashburn Mallory
Time of Service: 24th Great Lakes Regional Director, 1998-2002

Former Regional Director: Pamela L. Redden, MD
Time of Service: 25th Great Lakes Regional Director, 2002-2006

Former Regional Director: Schylbea Jean Hopkins
Time of Service: 26th Great Lakes Regional Director, 2006-2010

Former Regional Director: Charlene Truitt Nelson
Time of Service: 27th Great Lakes Regional Director, 2010-2014

Former Regional Director: Toni S. Kendrick
Time of Service: 28th Great Lakes Regional Director, 2014-2018

Former Regional Director: Carrie J. Clark
Time of Service: 29th Great Lakes Regional Director, 2018-2022

*Denotes deceased